A recent study from UC San Francisco has raised alarm about the impact of menopause on women with Multiple Sclerosis (MS), suggesting that the hormonal changes associated with menopause may worsen MS symptoms and accelerate its progression. This discovery sheds light on a concerning connection between menopause and MS, a neurological disorder that affects the outer sheath of the nerves, leading to symptoms like numbness, weakness, difficulty walking, and changes in vision.
MS is an autoimmune disease where the immune system mistakenly attacks myelin, the protective covering of nerve fibers, causing inflammation, injury, and the development of scar tissue (sclerosis). The condition disrupts communication between the brain and the rest of the body and can lead to irreversible nerve damage.
The UC San Francisco study focused on 184 women, tracking their health before and after menopause, and revealed that the decrease in estrogen during menopause has a significant negative effect on cognitive function, fine motor skills, and walking ability. The study also showed an increase in neurofilament light chain (NfL) biomarkers, a sign of nerve cell degeneration, which further confirmed the acceleration of MS progression after menopause.
The researchers found that after menopause, women with MS took longer to complete a 25-foot walk test, a component of the MS Functional Composite (MSFC), which also measures walking speed, cognition, and dexterity. These findings suggest that menopause may exacerbate the physical and cognitive impairments often seen in MS patients.
While MS predominantly affects women, the disease course can be influenced by hormonal changes, particularly those involving estrogen. As estrogen levels decline during menopause, researchers believe this may contribute to the worsening of MS symptoms.
In addition to the cognitive and mobility challenges, menopausal hot flashes can exacerbate heat sensitivity in some MS patients, which can make symptoms worse. Women may also face heightened difficulties with mood, sleep, fatigue, cognition, and bladder function during this period.
This study highlights the need for greater awareness of the intersection between menopause and MS, as well as targeted care strategies to address the unique challenges faced by women with MS as they navigate both conditions.
Related topics:
Health Ministry Report Reveals IVF Irregularities at Assuta Hospital, Calls for Systemic Reforms
Republicans Urged to Champion Family Rights and Access to Contraception and IVF in 2025 Agenda
Texas Woman Shares Joyful Pregnancy Announcement After Years of Struggles
